Entity Details

Primary name NLRC4
Entity type gene
Source Source Link

Details

PrimaryID58484
RefseqGeneNG_041780
SymbolNLRC4
NameNLR family CARD domain containing 4
Chromosome2
Location2p22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-11-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNLRC4_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000287 magnesium ion binding
GO:0002218 activation of innate immune response
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006954 inflammatory response
GO:0010954 positive regulation of protein processing
GO:0016045 detection of bacterium
GO:0032731 positive regulation of interleukin-1 beta production
GO:0042742 defense response to bacterium
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0045087 innate immune response
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051260 protein homooligomerization
GO:0061133 endopeptidase activator activity
GO:0070269 pyroptosis
GO:0072557 IPAF inflammasome complex
GO:0089720 caspase binding
GO:0097202 activation of cysteine-type endopeptidase activity

Diseases

Show/Hide Table