Entity Details

Primary name ZEB2
Entity type gene
Source Source Link

Details

PrimaryID9839
RefseqGeneNG_016431
SymbolZEB2
Namezinc finger E-box binding homeobox 2
Chromosome2
Location2q22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-04-07
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsZEB2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0019208 phosphatase regulator activity
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0043565 sequence-specific DNA binding
GO:0045636 positive regulation of melanocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048023 positive regulation of melanin biosynthetic process
GO:0048066 developmental pigmentation
GO:0048856 anatomical structure development
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0097324 melanocyte migration
GO:1903056 regulation of melanosome organization

Diseases

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Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
ZEB2SMAD2BioGRID, HPRD, MINT10400677 12714599 15231748 details
ZEB2SMAD3BioGRID, HPRD, IntAct, MINT10400677 12714599 15231748 16061479 19732720 details
ZEB2SMAD9BioGRID, HPRD, MINT15231748 details
ZEB2SMAD1BioGRID, HPRD, MINT10400677 12714599 15231748 22365546 details
ZEB2COPS6BioGRID, HPRD, IntAct16169070 details
ZEB2CTBP1BioGRID, HPRD, IntAct12714599 16061479 24722188 26186194 28514442 details
ZEB2MTA1BioGRID, IntAct18182442 26028330 details
ZEB2EHMT2IntAct26028330 details
ZEB2MTA2BioGRID, IntAct18182442 26028330 details
ZEB2APPBioGRID, IntAct21832049 31413325 details
ZEB2CBX4BioGRID16061479 details
ZEB2UBE2IBioGRID16061479 details
ZEB2SMAD5HPRD10400677 12714599 details
ZEB2CTBP2HPRD12714599 details
ZEB2SCHIP1IntAct20195357 details
ZEB2HDAC1BioGRID, IntAct18182442 26028330 details
ZEB2HDAC2BioGRID, IntAct18182442 26028330 details
ZEB2RBBP4BioGRID, IntAct18182442 26028330 details
ZEB2CEBPABioGRID17082780 details
ZEB2RBBP7BioGRID18182442 details
ZEB2HDAC4BioGRID16061479 details
ZEB2EP300BioGRID22365546 details
ZEB2FBXW7BioGRID30783098 details
ZEB2SUPT5HBioGRID29395067 details
ZEB2TEAD2BioGRID, MINT25609649 details
ZEB2MBD3IntAct26028330 details
ZEB2GATA3IntAct26028330 details
ZEB2MBD6IntAct26028330 details
ZEB2MTBPIntAct26028330 details
ZEB2CHD3IntAct26028330 details
ZEB2SOX2BioGRID, MINT23667531 details
ZEB2EZH2BioGRID27634302 details
ZEB2FBXO38BioGRID30804394 details
ZEB2KIF20ABioGRID31586073 details
ZEB2CUL4ABioGRID32235678 details
ZEB2TRIM37BioGRID32908313 details
ZEB2POLR1GBioGRID34079125 details
ZEB2MTA3IntAct26028330 details
ZEB2MEOX2IntAct20516212 details
ZEB2FOXP3IntAct29963231 details
ZEB2ELAVL1BioGRID19322201 details
ZEB2ZFP36BioGRID21784977 details
ZEB2VIRMABioGRID29507755 details
ZEB2DDX58BioGRID32513696 details