Entity Details

Primary name EIF3B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55884
EntryNameEIF3B_HUMAN
FullNameEukaryotic translation initiation factor 3 subunit B
TaxID9606
Evidenceevidence at protein level
Length814
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesEIF3B

GO terms

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GOName
GO:0001732 formation of cytoplasmic translation initiation complex
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005829 cytosol
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
GO:0016282 eukaryotic 43S preinitiation complex
GO:0031369 translation initiation factor binding
GO:0033290 eukaryotic 48S preinitiation complex
GO:0045202 synapse
GO:0060090 molecular adaptor activity
GO:0070062 extracellular exosome
GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m
GO:0075522 IRES-dependent viral translational initiation
GO:0075525 viral translational termination-reinitiation

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR011400 Eukaryotic translation initiation factor 3 subunit BFamilyFamily
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR013979 Translation initiation factor, beta propellor-like domainDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR034363 eIF3B, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

42 interactions

InteractorPartnerSourcesPublicationsLink
EIF3B_HUMANEIF3G_HUMANBioGRID, DIP, HPRD, IntAct, MINT, UniProt14688252 18599441 18628297 22863883 22939629 24396066 24981860 26186194 26344197 28514442 30021884 9822659 details
EIF3B_HUMANEIF3A_HUMANBioGRID, DIP, HPRD, IntAct, MINT, UniProt11169732 14519125 14688252 16541103 17469741 18599441 18628297 19245811 22939629 24981860 26344197 30573685 8995410 9822659 details
EIF3B_HUMANKS6B1_HUMANBioGRID, IntAct, UniProt16286006 18423201 21986499 24396066 details
EIF3B_HUMANPAIP1_HUMANBioGRID, MINT24396066 details
EIF3B_HUMANBRCA1_HUMANBioGRID22990118 26831064 details
EIF3B_HUMANACPM_HUMANBioGRID32296183 details
EIF3B_HUMANTBC23_HUMANBioGRID32296183 details
EIF3B_HUMANPBX4_HUMANBioGRID32296183 details
EIF3B_HUMANRBTN2_HUMANBioGRID32296183 details
EIF3B_HUMANTNNI1_HUMANBioGRID32296183 details
EIF3B_HUMANMERL_HUMANBioGRID32296183 details
EIF3B_HUMANBHLH9_HUMANBioGRID32296183 details
EIF3B_HUMANNREP_HUMANBioGRID25336651 details
EIF3B_HUMANEIF3I_HUMANBioGRID, DIP, HPRD, IntAct, UniProt14688252 16541103 18599441 18628297 22863883 22939629 24981860 26186194 26344197 28514442 details
EIF3B_HUMANEIF3J_HUMANBioGRID, HPRD, IntAct, UniProt14688252 15946946 18628297 details
EIF3B_HUMANRENT2_HUMANMINT17469741 details
EIF3B_HUMANIF4E_HUMANBioGRID, IntAct, MINT16541103 18423201 24981860 30573685 details
EIF3B_HUMANMTOR_HUMANBioGRID, IntAct16286006 18423201 21045808 details
EIF3B_HUMANEIF3F_HUMANBioGRID, DIP, IntAct, MINT, UniProt18599441 18628297 19245811 19615732 22939629 24396066 24981860 26186194 26344197 28514442 30573685 31527668 details
EIF3B_HUMANEIF3C_HUMANBioGRID, DIP, MINT, UniProt15946946 18599441 18628297 19245811 22939629 24981860 26344197 details
EIF3B_HUMANEIF3H_HUMANBioGRID, DIP, IntAct, UniProt18599441 18628297 19615732 22939629 24981860 26186194 26344197 28514442 32269044 details
EIF3B_HUMANDDX3X_HUMANBioGRID, UniProt18628297 29395067 details
EIF3B_HUMANEIF3K_HUMANBioGRID, DIP, UniProt18599441 18628297 22939629 24981860 26344197 details
EIF3B_HUMANEIF3E_HUMANBioGRID, DIP, IntAct, UniProt17403899 18599441 18628297 22939629 24981860 26344197 28514442 details
EIF3B_HUMANIF4G1_HUMANBioGRID, HPRD, MINT16541103 23023399 24981860 27381497 9418880 details
EIF3B_HUMANIF4A1_HUMANBioGRID, IntAct16541103 17053147 28514442 29395067 details
EIF3B_HUMANEIF3L_HUMANBioGRID, DIP, IntAct18599441 22939629 24981860 26344197 28514442 details
EIF3B_HUMANEIF3M_HUMANBioGRID, DIP, IntAct17403899 18599441 22939629 24981860 26186194 26344197 28514442 details
EIF3B_HUMANESR1_HUMANBioGRID, IntAct30573685 31527615 details
EIF3B_HUMANIF4B_HUMANBioGRID16286006 29228324 details
EIF3B_HUMANRS6_HUMANBioGRID16286006 27022092 details
EIF3B_HUMANIF6_HUMANBioGRID15946946 details
EIF3B_HUMANRPTOR_HUMANBioGRID16286006 21045808 details
EIF3B_HUMANSRRM2_HUMANBioGRID16159877 details
EIF3B_HUMANHDAC5_HUMANBioGRID21081666 details
EIF3B_HUMANIF4G3_HUMANBioGRID24981860 9418880 details
EIF3B_HUMANGAN_HUMANBioGRID26460568 details
EIF3B_HUMANUBC12_HUMANBioGRID27381497 28581483 details
EIF3B_HUMANP53_HUMANBioGRID29653964 32807901 details
EIF3B_HUMANSRSF3_HUMANBioGRID27381497 details
EIF3B_HUMANMTA70_HUMANBioGRID30232453 details
EIF3B_HUMANIL2RB_HUMANHPRD7693677 details