Entity Details

Primary name NIPBL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6KC79
EntryNameNIPBL_HUMAN
FullNameNipped-B-like protein
TaxID9606
Evidenceevidence at protein level
Length2804
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesNIPBL

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0001656 metanephros development
GO:0003007 heart morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006974 cellular response to DNA damage stimulus
GO:0007064 mitotic sister chromatid cohesion
GO:0007420 brain development
GO:0007605 sensory perception of sound
GO:0008022 protein C-terminus binding
GO:0019827 stem cell population maintenance
GO:0031065 positive regulation of histone deacetylation
GO:0032039 integrator complex
GO:0032116 SMC loading complex
GO:0034087 establishment of mitotic sister chromatid cohesion
GO:0034088 maintenance of mitotic sister chromatid cohesion
GO:0034613 cellular protein localization
GO:0035115 embryonic forelimb morphogenesis
GO:0035136 forelimb morphogenesis
GO:0035261 external genitalia morphogenesis
GO:0036033 mediator complex binding
GO:0040018 positive regulation of multicellular organism growth
GO:0042471 ear morphogenesis
GO:0042634 regulation of hair cycle
GO:0042826 histone deacetylase binding
GO:0043231 intracellular membrane-bounded organelle
GO:0045444 fat cell differentiation
GO:0045778 positive regulation of ossification
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045995 regulation of embryonic development
GO:0047485 protein N-terminus binding
GO:0048557 embryonic digestive tract morphogenesis
GO:0048565 digestive tract development
GO:0048589 developmental growth
GO:0048592 eye morphogenesis
GO:0048638 regulation of developmental growth
GO:0048703 embryonic viscerocranium morphogenesis
GO:0050890 cognition
GO:0060325 face morphogenesis
GO:0061010 gall bladder development
GO:0061038 uterus morphogenesis
GO:0070062 extracellular exosome
GO:0070087 chromo shadow domain binding
GO:0071169 establishment of protein localization to chromatin
GO:0071481 cellular response to X-ray
GO:0071733 obsolete transcriptional activation by promoter-enhancer looping
GO:0071921 cohesin loading
GO:0090694 Scc2-Scc4 cohesin loading complex
GO:1905406 positive regulation of mitotic cohesin loading
GO:1990414 replication-born double-strand break repair via sister chromatid exchange
GO:1990841 promoter-specific chromatin binding
GO:2001224 positive regulation of neuron migration

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR024986 Sister chromatid cohesion C-terminal domainDomainDomain
IPR026003 HEAT repeat associated with sister chromatid cohesion proteinRepeatRepeat
IPR033031 Scc2/Nipped-B familyFamilyFamily

Diseases

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