Entity Details

Primary name RIR2B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7LG56
EntryNameRIR2B_HUMAN
FullNameRibonucleoside-diphosphate reductase subunit M2 B
TaxID9606
Evidenceevidence at protein level
Length351
SequenceStatuscomplete
DateCreated2006-03-21
DateModified2021-06-02

Ontological Relatives

GenesRRM2B

GO terms

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GOName
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0009263 deoxyribonucleotide biosynthetic process
GO:0015949 nucleobase-containing small molecule interconversion
GO:0042802 identical protein binding
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000358 Ribonucleotide reductase small subunit familyFamilyFamily
IPR009078 Ferritin-like superfamilyFamilyHomologous superfamily
IPR012348 Ribonucleotide reductase-likeFamilyHomologous superfamily
IPR030475 Ribonucleotide reductase small subunit, acitve siteSiteActive site
IPR033909 Ribonucleotide reductase small subunitFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00242 CladribineDrugbanksmall molecule