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Entity Details
Primary name
LAX1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q8IWV1
EntryName
LAX1_HUMAN
FullName
Lymphocyte transmembrane adapter 1
TaxID
9606
Evidence
evidence at protein level
Length
398
SequenceStatus
complete
DateCreated
2005-12-20
DateModified
2021-06-02
Ontological Relatives
Genes
LAX1
GO terms
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GO
Name
GO:0000188
obsolete inactivation of MAPK activity
GO:0002250
adaptive immune response
GO:0005794
Golgi apparatus
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0006955
immune response
GO:0016020
membrane
GO:0016021
integral component of membrane
GO:0019901
protein kinase binding
GO:0035556
intracellular signal transduction
GO:0042113
B cell activation
GO:0042169
SH2 domain binding
GO:0046649
lymphocyte activation
GO:0050851
antigen receptor-mediated signaling pathway
GO:0050868
negative regulation of T cell activation
Subcellular Location
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Subcellular Location
Cell membrane
Domains
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Domain
Name
Category
Type
IPR031393
Lymphocyte transmembrane adapter 1
Family
Family
Diseases
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Drugs
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Interactions
12 interactions
Interactor
Partner
Sources
Publications
Link
LAX1_HUMAN
GRB7_HUMAN
BioGRID, IntAct
25416956
31515488
32296183
details
LAX1_HUMAN
STALP_HUMAN
BioGRID, IntAct
25416956
details
LAX1_HUMAN
NECD_HUMAN
BioGRID, IntAct
24722188
26871637
details
LAX1_HUMAN
IDHC_HUMAN
BioGRID
27229929
details
LAX1_HUMAN
RAB8A_HUMAN
MINT
24515439
details
LAX1_HUMAN
CTLA4_HUMAN
MINT
24515439
details
LAX1_HUMAN
TRI25_HUMAN
MINT
24515439
details
LAX1_HUMAN
GRB2_HUMAN
BioGRID, HPRD
12359715
details
LAX1_HUMAN
GRAP2_HUMAN
BioGRID, HPRD
12359715
details
LAX1_HUMAN
LCK_HUMAN
HPRD
12359715
details
LAX1_HUMAN
ZAP70_HUMAN
HPRD
12359715
details
LAX1_HUMAN
KSYK_HUMAN
HPRD
12359715
details
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