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Entity Details
Primary name
NPRL2_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q8WTW4
EntryName
NPRL2_HUMAN
FullName
GATOR complex protein NPRL2
TaxID
9606
Evidence
evidence at protein level
Length
380
SequenceStatus
complete
DateCreated
2004-05-10
DateModified
2021-06-02
Ontological Relatives
Genes
NPRL2
GO terms
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GO
Name
GO:0004672
protein kinase activity
GO:0005096
GTPase activator activity
GO:0005765
lysosomal membrane
GO:0006995
cellular response to nitrogen starvation
GO:0010508
positive regulation of autophagy
GO:0032007
negative regulation of TOR signaling
GO:0033673
negative regulation of kinase activity
GO:0034198
cellular response to amino acid starvation
GO:0043547
positive regulation of GTPase activity
GO:1990130
GATOR1 complex
GO:2000785
regulation of autophagosome assembly
Subcellular Location
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Subcellular Location
Lysosome membrane
Domains
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Domain
Name
Category
Type
IPR009348
Nitrogen permease regulator 2
Family
Family
Diseases
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Drugs
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Interactions
20 interactions
Interactor
Partner
Sources
Publications
Link
NPRL2_HUMAN
ANXA7_HUMAN
BioGRID, MINT
21900206
details
NPRL2_HUMAN
CDN1A_HUMAN
BioGRID, MINT
21900206
details
NPRL2_HUMAN
NPRL3_HUMAN
BioGRID, IntAct
19521502
23723238
27684187
28199306
28199315
28514442
details
NPRL2_HUMAN
DEPD5_HUMAN
BioGRID, DIP, IntAct
23723238
25263562
25366275
25936802
28199306
28199315
28514442
details
NPRL2_HUMAN
SZT2_HUMAN
BioGRID, IntAct
28199306
28199315
details
NPRL2_HUMAN
WDR24_HUMAN
BioGRID, IntAct
23723238
28199315
details
NPRL2_HUMAN
WDR59_HUMAN
BioGRID, IntAct
23723238
28199306
28199315
details
NPRL2_HUMAN
MIO_HUMAN
BioGRID, IntAct
28199306
28199315
details
NPRL2_HUMAN
LAMP1_HUMAN
BioGRID, IntAct
28199306
28199315
details
NPRL2_HUMAN
HS90A_HUMAN
BioGRID
22939624
details
NPRL2_HUMAN
SEH1_HUMAN
BioGRID
23723238
details
NPRL2_HUMAN
HERC2_HUMAN
BioGRID
25480944
details
NPRL2_HUMAN
RRAGA_HUMAN
BioGRID
25936802
26582740
details
NPRL2_HUMAN
RRAGD_HUMAN
BioGRID
26582740
details
NPRL2_HUMAN
KPTN_HUMAN
BioGRID
28199306
details
NPRL2_HUMAN
ITFG2_HUMAN
BioGRID
28199306
details
NPRL2_HUMAN
KICS2_HUMAN
BioGRID
28199306
details
NPRL2_HUMAN
RRAGC_HUMAN
BioGRID
26582740
details
NPRL2_HUMAN
RRAGB_HUMAN
BioGRID
26582740
details
NPRL2_HUMAN
RPTOR_HUMAN
BioGRID
26582740
details
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