Entity Details

Primary name CUX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14529
EntryNameCUX2_HUMAN
FullNameHomeobox protein cut-like 2
TaxID9606
Evidenceevidence at protein level
Length1486
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesCUX2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007614 short-term memory
GO:0010628 positive regulation of gene expression
GO:0043565 sequence-specific DNA binding
GO:0050775 positive regulation of dendrite morphogenesis
GO:0050890 cognition
GO:0051965 positive regulation of synapse assembly
GO:0061003 positive regulation of dendritic spine morphogenesis
GO:0070062 extracellular exosome
GO:0071310 cellular response to organic substance
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000463 positive regulation of excitatory postsynaptic potential

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR003350 CUT domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR010982 Lambda repressor-like, DNA-binding domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CUX2_HUMANCSK21_HUMANHPRD9446557 details