Entity Details

Primary name GHSR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92847
EntryNameGHSR_HUMAN
FullNameGrowth hormone secretagogue receptor type 1
TaxID9606
Evidenceevidence at protein level
Length366
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesGHSR

GO terms

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GOName
GO:0001616 growth hormone secretagogue receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005886 plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007283 spermatogenesis
GO:0007611 learning or memory
GO:0008154 actin polymerization or depolymerization
GO:0008343 adult feeding behavior
GO:0009725 response to hormone
GO:0009755 hormone-mediated signaling pathway
GO:0009986 cell surface
GO:0010700 negative regulation of norepinephrine secretion
GO:0016520 growth hormone-releasing hormone receptor activity
GO:0017046 peptide hormone binding
GO:0030252 growth hormone secretion
GO:0032094 response to food
GO:0032099 negative regulation of appetite
GO:0032100 positive regulation of appetite
GO:0032354 response to follicle-stimulating hormone
GO:0032355 response to estradiol
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032869 cellular response to insulin stimulus
GO:0036321 ghrelin secretion
GO:0040018 positive regulation of multicellular organism growth
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043134 regulation of hindgut contraction
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
GO:0045121 membrane raft
GO:0045923 positive regulation of fatty acid metabolic process
GO:0046676 negative regulation of insulin secretion
GO:0046697 decidualization
GO:0050728 negative regulation of inflammatory response
GO:0051963 regulation of synapse assembly
GO:0051969 regulation of transmission of nerve impulse
GO:0060123 regulation of growth hormone secretion
GO:0060416 response to growth hormone
GO:0071222 cellular response to lipopolysaccharide
GO:0071548 response to dexamethasone
GO:0090327 negative regulation of locomotion involved in locomotory behavior
GO:0097067 cellular response to thyroid hormone stimulus
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098696 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse
GO:0099170 postsynaptic modulation of chemical synaptic transmission
GO:0099175 regulation of postsynapse organization
GO:0099699 integral component of synaptic membrane
GO:0120058 positive regulation of small intestinal transit
GO:1903672 positive regulation of sprouting angiogenesis
GO:1904000 positive regulation of eating behavior
GO:1904008 response to monosodium glutamate
GO:1904349 positive regulation of small intestine smooth muscle contraction
GO:1905333 regulation of gastric motility
GO:1905564 positive regulation of vascular endothelial cell proliferation
GO:1990314 cellular response to insulin-like growth factor stimulus
GO:2000110 negative regulation of macrophage apoptotic process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR003905 Growth hormone secretagogue receptor/motilin receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR039129 Growth hormone secretagogue receptorFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB12128 UlimorelinDrugbanksmall molecule
DB13074 MacimorelinDrugbanksmall molecule
DB15488 EchinacosideDrugbanksmall molecule