Entity Details

Primary name NEIL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ969S2
EntryNameNEIL2_HUMAN
FullNameEndonuclease 8-like 2
TaxID9606
Evidenceevidence at protein level
Length332
SequenceStatuscomplete
DateCreated2004-12-07
DateModified2021-06-02

Ontological Relatives

GenesNEIL2

GO terms

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GOName
GO:0003684 damaged DNA binding
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006284 base-excision repair
GO:0008017 microtubule binding
GO:0008270 zinc ion binding
GO:0019104 DNA N-glycosylase activity
GO:0043231 intracellular membrane-bounded organelle
GO:0045008 depyrimidination
GO:0072686 mitotic spindle
GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000214 Zinc finger, DNA glycosylase/AP lyase-typeDomainDomain
IPR010979 Ribosomal protein S13-like, H2THFamilyHomologous superfamily
IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domainDomainDomain
IPR015886 DNA glycosylase/AP lyase, H2TH DNA-bindingDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01592 IronDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB14488 Ferrous gluconateDrugbanksmall molecule
DB14489 Ferrous succinateDrugbanksmall molecule
DB14490 Ferrous ascorbateDrugbanksmall molecule
DB14491 Ferrous fumarateDrugbanksmall molecule
DB14501 Ferrous glycine sulfateDrugbanksmall molecule