Entity Details

Primary name HDA10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ969S8
EntryNameHDA10_HUMAN
FullNamePolyamine deacetylase HDAC10
TaxID9606
Evidenceevidence at protein level
Length669
SequenceStatuscomplete
DateCreated2003-01-10
DateModified2021-06-02

Ontological Relatives

GenesHDAC10

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0004407 histone deacetylase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006281 DNA repair
GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-templated
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006476 protein deacetylation
GO:0008270 zinc ion binding
GO:0014003 oligodendrocyte development
GO:0016236 macroautophagy
GO:0016575 histone deacetylation
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0032425 positive regulation of mismatch repair
GO:0033558 protein deacetylase activity
GO:0034983 peptidyl-lysine deacetylation
GO:0035825 homologous recombination
GO:0042826 histone deacetylase binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0047609 acetylputrescine deacetylase activity
GO:0047611 acetylspermidine deacetylase activity
GO:0106047 polyamine deacetylation
GO:0106048 spermidine deacetylation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000286 Histone deacetylase familyFamilyFamily
IPR023696 Ureohydrolase domain superfamilyFamilyHomologous superfamily
IPR023801 Histone deacetylase domainDomainDomain
IPR037138 Histone deacetylase domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB05015 BelinostatDrugbanksmall molecule
DB06603 PanobinostatDrugbanksmall molecule
DB13346 BufexamacDrugbanksmall molecule