Entity Details

Primary name CERS2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96G23
EntryNameCERS2_HUMAN
FullNameCeramide synthase 2
TaxID9606
Evidenceevidence at protein level
Length380
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesCERS2

GO terms

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GOName
GO:0003677 DNA binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016410 N-acyltransferase activity
GO:0019216 regulation of lipid metabolic process
GO:0030148 sphingolipid biosynthetic process
GO:0046513 ceramide biosynthetic process
GO:0048681 negative regulation of axon regeneration
GO:0050291 sphingosine N-acyltransferase activity
GO:1900148 negative regulation of Schwann cell migration
GO:1905045 negative regulation of Schwann cell proliferation involved in axon regeneration

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR006634 TRAM/LAG1/CLN8 homology domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR016439 Sphingosine N-acyltransferase Lag1/Lac1-likeFamilyFamily

Diseases

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