Entity Details

Primary name PEO1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96RR1
EntryNamePEO1_HUMAN
FullNameTwinkle protein, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length684
SequenceStatuscomplete
DateCreated2005-10-25
DateModified2021-06-02

Ontological Relatives

GenesTWNK

GO terms

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GOName
GO:0002020 protease binding
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006264 mitochondrial DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006390 mitochondrial transcription
GO:0007005 mitochondrion organization
GO:0034214 protein hexamerization
GO:0042645 mitochondrial nucleoid
GO:0042802 identical protein binding
GO:0043139 5'-3' DNA helicase activity
GO:0071333 cellular response to glucose stimulus

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR007694 DNA helicase, DnaB-like, C-terminalDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR034154 Archaeal primase DnaG/twinkle, TOPRIM domainDomainDomain

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
PEO1_HUMANAKTIP_HUMANBioGRID, HPRD, IntAct16169070 details
PEO1_HUMANSMAD9_HUMANBioGRID, HPRD15231748 details
PEO1_HUMANSUMO2_HUMANIntAct16169070 details
PEO1_HUMANZBTB1_HUMANBioGRID24657165 details