Entity Details

Primary name SMC6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96SB8
EntryNameSMC6_HUMAN
FullNameStructural maintenance of chromosomes protein 6
TaxID9606
Evidenceevidence at protein level
Length1091
SequenceStatuscomplete
DateCreated2007-01-09
DateModified2021-06-02

Ontological Relatives

GenesSMC6

GO terms

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GOName
GO:0000722 telomere maintenance via recombination
GO:0000724 double-strand break repair via homologous recombination
GO:0000775 chromosome, centromeric region
GO:0000781 chromosome, telomeric region
GO:0000803 sex chromosome
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006974 cellular response to DNA damage stimulus
GO:0016605 PML body
GO:0016607 nuclear speck
GO:0030915 Smc5-Smc6 complex
GO:0031625 ubiquitin protein ligase binding
GO:0035061 interchromatin granule
GO:0035861 site of double-strand break
GO:0036121 double-stranded DNA helicase activity
GO:0051984 positive regulation of chromosome segregation
GO:0090398 cellular senescence
GO:0097431 mitotic spindle pole

Subcellular Location

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Subcellular Location
Chromosome
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR003395 RecF/RecN/SMC, N-terminalDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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