Entity Details

Primary name IMP2L_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96T52
EntryNameIMP2L_HUMAN
FullNameMitochondrial inner membrane protease subunit 2
TaxID9606
Evidenceevidence at protein level
Length175
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesIMMP2L

GO terms

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GOName
GO:0001541 ovarian follicle development
GO:0004252 serine-type endopeptidase activity
GO:0006465 signal peptide processing
GO:0006627 protein processing involved in protein targeting to mitochondrion
GO:0006801 superoxide metabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007283 spermatogenesis
GO:0007420 brain development
GO:0008015 blood circulation
GO:0008233 peptidase activity
GO:0016021 integral component of membrane
GO:0022904 respiratory electron transport chain
GO:0030728 ovulation
GO:0033108 mitochondrial respiratory chain complex assembly
GO:0042720 mitochondrial inner membrane peptidase complex
GO:0061300 cerebellum vasculature development

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR000223 Peptidase S26A, signal peptidase IFamilyFamily
IPR019533 Peptidase S26DomainDomain
IPR019758 Peptidase S26A, signal peptidase I, conserved siteSiteConserved site
IPR036286 LexA/Signal peptidase-like superfamilyFamilyHomologous superfamily
IPR037730 Mitochondrial inner membrane protease subunit 2FamilyFamily

Diseases

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Disease IDSourceNameDescription
137580 OMIMGilles de la Tourette syndrome (GTS)Neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities. The disease may be caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
IMP2L_HUMANLITAF_HUMANIntAct32814053 details
IMP2L_HUMANHNRPD_HUMANBioGRID15231747 details