Entity Details

Primary name ANGP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15123
EntryNameANGP2_HUMAN
FullNameAngiopoietin-2
TaxID9606
Evidenceevidence at protein level
Length496
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesANGPT2

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001666 response to hypoxia
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007281 germ cell development
GO:0009314 response to radiation
GO:0009612 response to mechanical stimulus
GO:0009749 response to glucose
GO:0010467 gene expression
GO:0010812 negative regulation of cell-substrate adhesion
GO:0014070 response to organic cyclic compound
GO:0014823 response to activity
GO:0016525 negative regulation of angiogenesis
GO:0030971 receptor tyrosine kinase binding
GO:0031100 animal organ regeneration
GO:0042995 cell projection
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0045766 positive regulation of angiogenesis
GO:0046872 metal ion binding
GO:0048014 Tie signaling pathway
GO:0050900 leukocyte migration
GO:0050928 negative regulation of positive chemotaxis
GO:0060135 maternal process involved in female pregnancy
GO:0062023 collagen-containing extracellular matrix
GO:0071363 cellular response to growth factor stimulus
GO:0072012 glomerulus vasculature development

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domainDomainDomain
IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1FamilyHomologous superfamily
IPR020837 Fibrinogen, conserved siteSiteConserved site
IPR028844 Angiopoietin-2FamilyFamily
IPR036056 Fibrinogen-like, C-terminalFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB15303 FaricimabDrugbankbiotech