Entity Details

Primary name LRAD4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15165
EntryNameLRAD4_HUMAN
FullNameLow-density lipoprotein receptor class A domain-containing protein 4
TaxID9606
Evidenceevidence at protein level
Length306
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesLDLRAD4

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010991 negative regulation of SMAD protein complex assembly
GO:0016021 integral component of membrane
GO:0030336 negative regulation of cell migration
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031901 early endosome membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0070412 R-SMAD binding

Subcellular Location

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Subcellular Location
Early endosome membrane

Domains

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DomainNameCategoryType
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved siteSiteConserved site
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily
IPR043445 TMEPAI familyFamilyFamily

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
LRAD4_HUMANAP2C_HUMANIntAct24835590 details
LRAD4_HUMANZDH22_HUMANBioGRID, IntAct32296183 details
LRAD4_HUMANSGTA_HUMANBioGRID, IntAct32296183 details
LRAD4_HUMANGET3_HUMANBioGRID, IntAct32296183 details