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Entity Details
Primary name
PKHG2_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9H7P9
EntryName
PKHG2_HUMAN
FullName
Pleckstrin homology domain-containing family G member 2
TaxID
9606
Evidence
evidence at protein level
Length
1386
SequenceStatus
complete
DateCreated
2007-10-02
DateModified
2021-06-02
Ontological Relatives
Genes
PLEKHG2
GO terms
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GO
Name
GO:0005085
guanyl-nucleotide exchange factor activity
GO:0005829
cytosol
GO:0007186
G protein-coupled receptor signaling pathway
GO:0030833
regulation of actin filament polymerization
GO:0043065
positive regulation of apoptotic process
GO:0051056
regulation of small GTPase mediated signal transduction
Subcellular Location
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Domains
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Domain
Name
Category
Type
IPR000219
Dbl homology (DH) domain
Domain
Domain
IPR001849
Pleckstrin homology domain
Domain
Domain
IPR011993
PH-like domain superfamily
Family
Homologous superfamily
IPR035899
Dbl homology (DH) domain superfamily
Family
Homologous superfamily
IPR043324
PKHG1/2/3, pleckstrin homology (PH) domain
Domain
Domain
Diseases
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Drugs
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Interactions
14 interactions
Interactor
Partner
Sources
Publications
Link
PKHG2_HUMAN
PIN1_HUMAN
BioGRID, IntAct
32296183
details
PKHG2_HUMAN
ACTN3_HUMAN
BioGRID, IntAct
25416956
29892012
details
PKHG2_HUMAN
RAC1_HUMAN
BioGRID, HPRD
11839748
details
PKHG2_HUMAN
CDC42_HUMAN
BioGRID, HPRD
11839748
details
PKHG2_HUMAN
RHOA_HUMAN
BioGRID, HPRD
11839748
details
PKHG2_HUMAN
GBB1_HUMAN
BioGRID
18045877
27765816
details
PKHG2_HUMAN
GBG2_HUMAN
BioGRID
18045877
details
PKHG2_HUMAN
A4_HUMAN
BioGRID
21244100
21832049
details
PKHG2_HUMAN
XRN1_HUMAN
BioGRID
15231747
details
PKHG2_HUMAN
FHL1_HUMAN
BioGRID
27765816
28489964
details
PKHG2_HUMAN
GNAS3_HUMAN
BioGRID
28489964
details
PKHG2_HUMAN
GNAS2_HUMAN
BioGRID
28489964
details
PKHG2_HUMAN
ALEX_HUMAN
BioGRID
28489964
details
PKHG2_HUMAN
GNAS1_HUMAN
BioGRID
28489964
details
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