Entity Details
| Primary name |
SPCS_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q9HD40 |
| EntryName | SPCS_HUMAN |
| FullName | O-phosphoseryl-tRNA(Sec) selenium transferase |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 501 |
| SequenceStatus | complete |
| DateCreated | 2005-03-29 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Cytoplasm |
Domains
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| Domain | Name | Category | Type |
| IPR008829 | SepSecS/SepCysS family | Family | Family |
| IPR015421 | Pyridoxal phosphate-dependent transferase, major domain | Family | Homologous superfamily |
| IPR015424 | Pyridoxal phosphate-dependent transferase | Family | Homologous superfamily |
| IPR019793 | Peroxidases heam-ligand binding site | Site | Binding site |
| IPR019872 | O-phosphoseryl-tRNA(Sec) selenium transferase | Family | Family |
Diseases
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| Disease ID | Source | Name | Description |
| 613811 | OMIM | Pontocerebellar hypoplasia 2D (PCH2D) | A disorder characterized by postnatal onset of progressive atrophy of the cerebrum and cerebellum, microcephaly, profound mental retardation, spasticity, and variable seizures. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB00114 | Pyridoxal phosphate | Drugbank | small molecule |
Interactions
2 interactions