Entity Details

Primary name MYO10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HD67
EntryNameMYO10_HUMAN
FullNameUnconventional myosin-X
TaxID9606
Evidenceevidence at protein level
Length2058
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesMYO10

GO terms

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GOName
GO:0001726 ruffle
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0008360 regulation of cell shape
GO:0016459 myosin complex
GO:0030027 lamellipodium
GO:0030507 spectrin binding
GO:0030705 cytoskeleton-dependent intracellular transport
GO:0031527 filopodium membrane
GO:0032433 filopodium tip
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0051015 actin filament binding
GO:0051489 regulation of filopodium assembly
GO:0060002 plus-end directed microfilament motor activity

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR000159 Ras-associating (RA) domainDomainDomain
IPR000299 FERM domainDomainDomain
IPR000857 MyTH4 domainDomainDomain
IPR001609 Myosin head, motor domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031971 Unconventional myosin-X, coiled coil domainDomainDomain
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR036124 Class X myosin, motor domainDomainDomain
IPR036961 Kinesin motor domain superfamilyFamilyHomologous superfamily
IPR038185 MyTH4 domain superfamilyFamilyHomologous superfamily
IPR040640 Myosin X, N-terminal SH3 domainDomainDomain
IPR041797 Myosin X, FERM domain C-lobeDomainDomain

Diseases

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