Entity Details

Primary name PDGFC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NRA1
EntryNamePDGFC_HUMAN
FullNamePlatelet-derived growth factor C
TaxID9606
Evidenceevidence at protein level
Length345
SequenceStatuscomplete
DateCreated2008-07-22
DateModified2021-06-02

Ontological Relatives

GenesPDGFC

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0005161 platelet-derived growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005788 endoplasmic reticulum lumen
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity
GO:0007417 central nervous system development
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0009887 animal organ morphogenesis
GO:0009986 cell surface
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0030335 positive regulation of cell migration
GO:0031954 positive regulation of protein autophosphorylation
GO:0042803 protein homodimerization activity
GO:0043406 positive regulation of MAP kinase activity
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048146 positive regulation of fibroblast proliferation
GO:0048565 digestive tract development
GO:0048568 embryonic organ development
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:0051781 positive regulation of cell division
GO:0060348 bone development
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070851 growth factor receptor binding
GO:0071230 cellular response to amino acid stimulus
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Cytoplasmic granule
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR000072 PDGF/VEGF domainDomainDomain
IPR000859 CUB domainDomainDomain
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily
IPR029817 Platelet-derived growth factor CFamilyFamily
IPR035914 Spermadhesin, CUB domain superfamilyFamilyHomologous superfamily

Diseases

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