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Entity Details
Primary name
SEPT4_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
O43236
EntryName
SEPT4_HUMAN
FullName
Septin-4
TaxID
9606
Evidence
evidence at protein level
Length
478
SequenceStatus
complete
DateCreated
1998-07-15
DateModified
2021-06-02
Ontological Relatives
Genes
SEPTIN4
GO terms
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GO
Name
GO:0000287
magnesium ion binding
GO:0003924
GTPase activity
GO:0005198
structural molecule activity
GO:0005525
GTP binding
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005739
mitochondrion
GO:0005741
mitochondrial outer membrane
GO:0005829
cytosol
GO:0005940
septin ring
GO:0006915
apoptotic process
GO:0007283
spermatogenesis
GO:0008021
synaptic vesicle
GO:0015630
microtubule cytoskeleton
GO:0017157
regulation of exocytosis
GO:0030154
cell differentiation
GO:0031105
septin complex
GO:0031398
positive regulation of protein ubiquitination
GO:0032153
cell division site
GO:0034613
cellular protein localization
GO:0042802
identical protein binding
GO:0042981
regulation of apoptotic process
GO:0043065
positive regulation of apoptotic process
GO:0060090
molecular adaptor activity
GO:0061640
cytoskeleton-dependent cytokinesis
GO:0097227
sperm annulus
GO:2001244
positive regulation of intrinsic apoptotic signaling pathway
Subcellular Location
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Subcellular Location
Cell projection
Cytoplasm
Cytoplasmic vesicle
Mitochondrion
Nucleus
Domains
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Domain
Name
Category
Type
IPR016491
Septin
Family
Family
IPR027417
P-loop containing nucleoside triphosphate hydrolase
Family
Homologous superfamily
IPR030379
Septin-type guanine nucleotide-binding (G) domain
Domain
Domain
Diseases
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Drugs
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Interactions
26 interactions
Interactor
Partner
Sources
Publications
Link
SEPT4_HUMAN
SEP14_HUMAN
IntAct
17922164
details
SEPT4_HUMAN
XIAP_HUMAN
BioGRID, IntAct
15029247
21185211
21869827
22185822
28224479
29020630
details
SEPT4_HUMAN
SEP12_HUMAN
BioGRID, IntAct, UniProt
25588830
25775403
26186194
28514442
details
SEPT4_HUMAN
DYL1_HUMAN
BioGRID, IntAct
32296183
details
SEPT4_HUMAN
DYL2_HUMAN
BioGRID, IntAct
32296183
details
SEPT4_HUMAN
SEPT4_HUMAN
HPRD, UniProt
15214843
details
SEPT4_HUMAN
SEPT5_HUMAN
HPRD, UniProt
15214843
details
SEPT4_HUMAN
SEPT8_HUMAN
HPRD, UniProt
15116257
15214843
details
SEPT4_HUMAN
A4_HUMAN
IntAct
32814053
details
SEPT4_HUMAN
SYUA_HUMAN
BioGRID, IntAct
12695511
17893145
32814053
details
SEPT4_HUMAN
HD_HUMAN
IntAct
32814053
details
SEPT4_HUMAN
AREL1_HUMAN
BioGRID
23479728
details
SEPT4_HUMAN
BCL2_HUMAN
BioGRID
29020630
details
SEPT4_HUMAN
PRKN_HUMAN
HPRD
14559152
details
SEPT4_HUMAN
TNIK_HUMAN
IntAct
17353931
details
SEPT4_HUMAN
NR4A1_HUMAN
IntAct
20195357
details
SEPT4_HUMAN
RB_HUMAN
IntAct
20195357
details
SEPT4_HUMAN
SIAH1_HUMAN
BioGRID, IntAct
21185211
details
SEPT4_HUMAN
FMR1_HUMAN
IntAct
31413325
details
SEPT4_HUMAN
TSC2_HUMAN
MINT
21653829
details
SEPT4_HUMAN
BIRC3_HUMAN
BioGRID
21869827
details
SEPT4_HUMAN
UBC_HUMAN
BioGRID
28224479
details
SEPT4_HUMAN
WWP2_HUMAN
BioGRID
31924572
details
SEPT4_HUMAN
PARP1_HUMAN
BioGRID
31924572
details
SEPT4_HUMAN
SYUB_HUMAN
HPRD
12695511
details
SEPT4_HUMAN
SNCAP_HUMAN
HPRD
12695511
details
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