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Entity Details
Primary name
SRGP3_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
O43295
EntryName
SRGP3_HUMAN
FullName
SLIT-ROBO Rho GTPase-activating protein 3
TaxID
9606
Evidence
evidence at protein level
Length
1099
SequenceStatus
complete
DateCreated
1998-07-15
DateModified
2021-06-02
Ontological Relatives
Genes
SRGAP3
GO terms
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GO
Name
GO:0005096
GTPase activator activity
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0007165
signal transduction
GO:0030336
negative regulation of cell migration
GO:0043547
positive regulation of GTPase activity
GO:0051056
regulation of small GTPase mediated signal transduction
Subcellular Location
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Domains
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Domain
Name
Category
Type
IPR000198
Rho GTPase-activating protein domain
Domain
Domain
IPR001060
FCH domain
Domain
Domain
IPR001452
SH3 domain
Domain
Domain
IPR008936
Rho GTPase activation protein
Family
Homologous superfamily
IPR027267
AH/BAR domain superfamily
Family
Homologous superfamily
IPR031160
F-BAR domain
Domain
Domain
IPR035648
srGAP1/2/3, SH3 domain
Domain
Domain
IPR036028
SH3-like domain superfamily
Family
Homologous superfamily
Diseases
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Drugs
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Interactions
18 interactions
Interactor
Partner
Sources
Publications
Link
SRGP3_HUMAN
TNIK_HUMAN
BioGRID, IntAct
17043677
31413325
details
SRGP3_HUMAN
TNFL6_HUMAN
BioGRID, IntAct
19807924
details
SRGP3_HUMAN
SUV91_HUMAN
BioGRID, MINT
23455924
details
SRGP3_HUMAN
KDM1A_HUMAN
BioGRID, MINT
23455924
details
SRGP3_HUMAN
ANM6_HUMAN
BioGRID, MINT
23455924
details
SRGP3_HUMAN
HD_HUMAN
IntAct
17500595
details
SRGP3_HUMAN
GRB2_HUMAN
MINT
25819436
details
SRGP3_HUMAN
DISC1_HUMAN
BioGRID, IntAct
17043677
31413325
details
SRGP3_HUMAN
DTBP1_HUMAN
BioGRID
17043677
details
SRGP3_HUMAN
ENKD1_HUMAN
BioGRID
32296183
details
SRGP3_HUMAN
RAC1_HUMAN
BioGRID
32203420
details
SRGP3_HUMAN
SH3G2_HUMAN
MINT
25819436
details
SRGP3_HUMAN
SH3G1_HUMAN
MINT
25819436
details
SRGP3_HUMAN
SRGP3_HUMAN
MINT
25819436
details
SRGP3_HUMAN
FMR1_HUMAN
IntAct
31413325
details
SRGP3_HUMAN
RHG24_HUMAN
BioGRID, IntAct
32203420
details
SRGP3_HUMAN
SMRC2_HUMAN
HPRD
12368262
details
SRGP3_HUMAN
WASF1_HUMAN
HPRD
12447388
details
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