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Entity Details
Primary name
KLHL3_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9UH77
EntryName
KLHL3_HUMAN
FullName
Kelch-like protein 3
TaxID
9606
Evidence
evidence at protein level
Length
587
SequenceStatus
complete
DateCreated
2001-04-27
DateModified
2021-06-02
Ontological Relatives
Genes
KLHL3
GO terms
Show/Hide Table
GO
Name
GO:0003779
actin binding
GO:0005198
structural molecule activity
GO:0005829
cytosol
GO:0005856
cytoskeleton
GO:0006511
ubiquitin-dependent protein catabolic process
GO:0016567
protein ubiquitination
GO:0031463
Cul3-RING ubiquitin ligase complex
GO:0043687
post-translational protein modification
GO:0050801
ion homeostasis
GO:0061912
selective autophagy
GO:0070294
renal sodium ion absorption
GO:0070936
protein K48-linked ubiquitination
GO:0072156
distal tubule morphogenesis
GO:0097602
cullin family protein binding
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR000210
BTB/POZ domain
Domain
Domain
IPR006652
Kelch repeat type 1
Repeat
Repeat
IPR011333
SKP1/BTB/POZ domain superfamily
Family
Homologous superfamily
IPR011705
BTB/Kelch-associated
Domain
Domain
IPR015915
Kelch-type beta propeller
Family
Homologous superfamily
IPR017096
BTB-kelch protein
Family
Family
IPR030578
Kelch-like protein 3
Family
Family
Diseases
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Drugs
Show/Hide Table
Interactions
32 interactions
Interactor
Partner
Sources
Publications
Link
KLHL3_HUMAN
CUL3_HUMAN
BioGRID, IntAct, MINT
23387299
23453970
23573258
23576762
23665031
23838290
25250572
25416956
25502805
26100637
26286618
30819806
31515488
32296183
details
KLHL3_HUMAN
WNK4_HUMAN
BioGRID, MINT
23453970
23576762
23665031
23838290
23962426
24641320
25313067
26286618
26349538
26435498
details
KLHL3_HUMAN
KLH12_HUMAN
BioGRID, IntAct
25416956
32296183
details
KLHL3_HUMAN
KLHL2_HUMAN
BioGRID, IntAct
28514442
32296183
details
KLHL3_HUMAN
TNPO2_HUMAN
BioGRID, IntAct
32296183
details
KLHL3_HUMAN
KEAP1_HUMAN
BioGRID, IntAct
25416956
32296183
details
KLHL3_HUMAN
CASP6_HUMAN
IntAct
32814053
details
KLHL3_HUMAN
FGFR3_HUMAN
IntAct
32814053
details
KLHL3_HUMAN
GELS_HUMAN
IntAct
32814053
details
KLHL3_HUMAN
RASH_HUMAN
IntAct
32814053
details
KLHL3_HUMAN
LAMP2_HUMAN
IntAct
32814053
details
KLHL3_HUMAN
KLF11_HUMAN
IntAct
32814053
details
KLHL3_HUMAN
DNJB6_HUMAN
IntAct
32814053
details
KLHL3_HUMAN
WNK1_HUMAN
BioGRID
23387299
23576762
23838290
26286618
29904119
details
KLHL3_HUMAN
WNK3_HUMAN
BioGRID
23387299
23838290
24641320
details
KLHL3_HUMAN
KLHL3_HUMAN
BioGRID
23387299
25416956
details
KLHL3_HUMAN
MO4L2_HUMAN
BioGRID
25416956
details
KLHL3_HUMAN
CF206_HUMAN
BioGRID
25416956
details
KLHL3_HUMAN
KAPCA_HUMAN
BioGRID
26435498
details
KLHL3_HUMAN
AKT1_HUMAN
BioGRID
26435498
details
KLHL3_HUMAN
PP2BA_HUMAN
BioGRID
30718414
details
KLHL3_HUMAN
S12A3_HUMAN
BioGRID
22406640
details
KLHL3_HUMAN
WNK2_HUMAN
BioGRID
23387299
23838290
details
KLHL3_HUMAN
RBX1_HUMAN
BioGRID
23387299
details
KLHL3_HUMAN
CLD8_HUMAN
BioGRID
25831548
details
KLHL3_HUMAN
SQSTM_HUMAN
BioGRID
26349538
details
KLHL3_HUMAN
SOX9_HUMAN
BioGRID
33173725
details
KLHL3_HUMAN
OPRD_HUMAN
HPRD
11259487
details
KLHL3_HUMAN
SYT2_HUMAN
HPRD
10734137
details
KLHL3_HUMAN
HNRPQ_HUMAN
HPRD
10734137
details
KLHL3_HUMAN
GNAI1_HUMAN
HPRD
11259487
details
KLHL3_HUMAN
GNAO_HUMAN
HPRD
11259487
details
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