Entity Details

Primary name FBX5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UKT4
EntryNameFBX5_HUMAN
FullNameF-box only protein 5
TaxID9606
Evidenceevidence at protein level
Length447
SequenceStatuscomplete
DateCreated2002-11-01
DateModified2021-06-02

Ontological Relatives

GenesFBXO5

GO terms

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GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0001556 oocyte maturation
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005829 cytosol
GO:0006275 regulation of DNA replication
GO:0007057 spindle assembly involved in female meiosis I
GO:0007088 regulation of mitotic nuclear division
GO:0007346 regulation of mitotic cell cycle
GO:0008284 positive regulation of cell population proliferation
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0010997 anaphase-promoting complex binding
GO:0016050 vesicle organization
GO:0016567 protein ubiquitination
GO:0019901 protein kinase binding
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0032876 negative regulation of DNA endoreduplication
GO:0045669 positive regulation of osteoblast differentiation
GO:0045835 negative regulation of meiotic nuclear division
GO:0045841 negative regulation of mitotic metaphase/anaphase transition
GO:0046785 microtubule polymerization
GO:0046872 metal ion binding
GO:0051301 cell division
GO:0051444 negative regulation of ubiquitin-protein transferase activity
GO:0070169 positive regulation of biomineral tissue development
GO:0072687 meiotic spindle
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1904667 negative regulation of ubiquitin protein ligase activity
GO:1905322 positive regulation of mesenchymal stem cell migration
GO:1990948 ubiquitin ligase inhibitor activity
GO:2000773 negative regulation of cellular senescence
GO:2001021 negative regulation of response to DNA damage stimulus

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001810 F-box domainDomainDomain
IPR044064 Zinc finger ZBR-type domainDomainDomain

Diseases

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Interactions

23 interactions

InteractorPartnerSourcesPublicationsLink
FBX5_HUMANEVI5_HUMANBioGRID, HPRD, IntAct16439210 details
FBX5_HUMANPLK1_HUMANBioGRID, IntAct15469984 16439210 details
FBX5_HUMANSKP1_HUMANBioGRID, HPRD, IntAct, MINT10531035 17380122 17463251 27705803 31130363 31257023 32296183 details
FBX5_HUMANCDC27_HUMANBioGRID, DIP, IntAct16921029 17719540 18662541 21454540 23708001 28514442 32076268 details
FBX5_HUMANCDC16_HUMANBioGRID, IntAct16921029 20360068 26496610 details
FBX5_HUMANTPM3_HUMANBioGRID, IntAct21988832 details
FBX5_HUMANCDC23_HUMANBioGRID, DIP, IntAct16921029 23708001 26496610 details
FBX5_HUMANFBW1A_HUMANBioGRID, IntAct12791267 15469984 25900982 26091241 28514442 details
FBX5_HUMANFZR1_HUMANBioGRID, DIP, HPRD, IntAct11751633 11988738 16921029 23708001 28514442 29875408 details
FBX5_HUMANANC2_HUMANBioGRID, DIP16921029 23708001 26083744 34079125 details
FBX5_HUMANAPC10_HUMANDIP23708001 details
FBX5_HUMANAPC4_HUMANBioGRID, DIP16921029 25750436 26083744 details
FBX5_HUMANCDC20_HUMANBioGRID, HPRD11389834 11751633 11976684 11988738 25750436 details
FBX5_HUMANCDK1_HUMANBioGRID21454540 details
FBX5_HUMANAPC1_HUMANBioGRID16921029 details
FBX5_HUMANAPC5_HUMANBioGRID16921029 details
FBX5_HUMANAPC7_HUMANBioGRID16921029 details
FBX5_HUMANAPC11_HUMANBioGRID16921029 details
FBX5_HUMANSRC_HUMANBioGRID20717963 details
FBX5_HUMANFBW1B_HUMANBioGRID12791267 22017875 25332235 details
FBX5_HUMANBRCA1_HUMANBioGRID23086937 details
FBX5_HUMANBARD1_HUMANBioGRID23086937 details
FBX5_HUMANCUL1_HUMANBioGRID29103612 details