Entity Details

Primary name FAN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y2M0
EntryNameFAN1_HUMAN
FullNameFanconi-associated nuclease 1
TaxID9606
Evidenceevidence at protein level
Length1017
SequenceStatuscomplete
DateCreated2007-11-13
DateModified2021-06-02

Ontological Relatives

GenesFAN1

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0000724 double-strand break repair via homologous recombination
GO:0004528 phosphodiesterase I activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0008409 5'-3' exonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0033683 nucleotide-excision repair, DNA incision
GO:0036297 interstrand cross-link repair
GO:0045171 intercellular bridge
GO:0070336 flap-structured DNA binding
GO:0140036 ubiquitin-dependent protein binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR006642 Rad18, zinc finger UBZ4-typeDomainDomain
IPR011856 tRNA endonuclease-like domain superfamilyFamilyHomologous superfamily
IPR014883 VRR-NUC domainDomainDomain
IPR033315 Fanconi-associated nuclease 1-likeFamilyFamily

Diseases

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