Entity Details

Primary name DYRK3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43781
EntryNameDYRK3_HUMAN
FullNameDual specificity tyrosine-phosphorylation-regulated kinase 3
TaxID9606
Evidenceevidence at protein level
Length588
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesDYRK3

GO terms

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GOName
GO:0000242 pericentriolar material
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0006468 protein phosphorylation
GO:0007049 cell cycle
GO:0010494 cytoplasmic stress granule
GO:0016607 nuclear speck
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0030218 erythrocyte differentiation
GO:0035063 nuclear speck organization
GO:0035617 stress granule disassembly
GO:0043066 negative regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0051301 cell division
GO:0080135 regulation of cellular response to stress
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902751 positive regulation of cell cycle G2/M phase transition
GO:1903008 organelle disassembly
GO:1903432 regulation of TORC1 signaling

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic granule
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR042521 Dual specificity tyrosine-phosphorylation-regulated kinaseFamilyHomologous superfamily

Diseases

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