Entity Details

Primary name MMP24_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y5R2
EntryNameMMP24_HUMAN
FullNameMatrix metalloproteinase-24
TaxID9606
Evidenceevidence at transcript level
Length645
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesMMP24

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005887 integral component of plasma membrane
GO:0006508 proteolysis
GO:0008047 enzyme activator activity
GO:0008270 zinc ion binding
GO:0010001 glial cell differentiation
GO:0030198 extracellular matrix organization
GO:0030574 collagen catabolic process
GO:0031012 extracellular matrix
GO:0032588 trans-Golgi network membrane
GO:0044331 cell-cell adhesion mediated by cadherin
GO:0045296 cadherin binding
GO:0050965 detection of temperature stimulus involved in sensory perception of pain
GO:0070062 extracellular exosome
GO:0097150 neuronal stem cell population maintenance
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules

Subcellular Location

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Subcellular Location
Cell membrane
Golgi apparatus
Secreted

Domains

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DomainNameCategoryType
IPR000585 Hemopexin-like domainDomainDomain
IPR001818 Peptidase M10, metallopeptidaseDomainDomain
IPR002477 Peptidoglycan binding-likeDomainDomain
IPR006026 Peptidase, metallopeptidaseDomainDomain
IPR018486 Hemopexin, conserved siteSiteConserved site
IPR018487 Hemopexin-like repeatsRepeatRepeat
IPR021190 Peptidase M10AFamilyFamily
IPR021805 Peptidase M10A, matrix metallopeptidase, C-terminalDomainDomain
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR028723 Matrix metalloproteinase-24FamilyFamily
IPR033739 Peptidase M10A, catalytic domainDomainDomain
IPR036365 PGBD-like superfamilyFamilyHomologous superfamily
IPR036375 Hemopexin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00786 MarimastatDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
MMP24_HUMANBUD31_HUMANBioGRID, MINT28298427 details
MMP24_HUMANKISS1_HUMANHPRD12879005 details