Entity Details

Primary name UBP16_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y5T5
EntryNameUBP16_HUMAN
FullNameUbiquitin carboxyl-terminal hydrolase 16
TaxID9606
Evidenceevidence at protein level
Length823
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesUSP16

GO terms

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GOName
GO:0000278 mitotic cell cycle
GO:0003713 transcription coactivator activity
GO:0004197 cysteine-type endopeptidase activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0008270 zinc ion binding
GO:0016578 histone deubiquitination
GO:0016579 protein deubiquitination
GO:0035522 monoubiquitinated histone H2A deubiquitination
GO:0042393 histone binding
GO:0043130 ubiquitin binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045901 positive regulation of translational elongation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051289 protein homotetramerization
GO:0051301 cell division
GO:0051726 regulation of cell cycle
GO:0070537 histone H2A K63-linked deubiquitination
GO:0140014 mitotic nuclear division

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolaseDomainDomain
IPR001607 Zinc finger, UBP-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR018200 Ubiquitin specific protease, conserved siteSiteConserved site
IPR028889 Ubiquitin specific protease domainDomainDomain
IPR030849 Ubiquitin carboxyl-terminal hydrolase 16FamilyFamily
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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