Entity Details

Primary name TNR11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y6Q6
EntryNameTNR11_HUMAN
FullNameTumor necrosis factor receptor superfamily member 11A
TaxID9606
Evidenceevidence at protein level
Length616
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesTNFRSF11A

GO terms

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GOName
GO:0001503 ossification
GO:0002250 adaptive immune response
GO:0002548 monocyte chemotaxis
GO:0004888 transmembrane signaling receptor activity
GO:0005031 tumor necrosis factor-activated receptor activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008284 positive regulation of cell population proliferation
GO:0009314 response to radiation
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0019955 cytokine binding
GO:0030316 osteoclast differentiation
GO:0032496 response to lipopolysaccharide
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0034097 response to cytokine
GO:0034612 response to tumor necrosis factor
GO:0038023 signaling receptor activity
GO:0043507 positive regulation of JUN kinase activity
GO:0045780 positive regulation of bone resorption
GO:0046872 metal ion binding
GO:0048535 lymph node development
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060086 circadian temperature homeostasis
GO:0060749 mammary gland alveolus development
GO:0070555 response to interleukin-1
GO:0071812 positive regulation of fever generation by positive regulation of prostaglandin secretion
GO:0071847 TNFSF11-mediated signaling pathway
GO:0071848 positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
GO:0072674 multinuclear osteoclast differentiation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001368 TNFR/NGFR cysteine-rich regionDomainDomain
IPR022323 Tumour necrosis factor receptor 11FamilyFamily
IPR022361 Tumour necrosis factor receptor 11AFamilyFamily
IPR034040 Tumor necrosis factor receptor 11A, N-terminalDomainDomain
IPR041648 Rank, cysteine-rich repeat domain 2DomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB05959 ENMD-1198Drugbanksmall molecule