Entity Details

Primary name SEM7A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75326
EntryNameSEM7A_HUMAN
FullNameSemaphorin-7A
TaxID9606
Evidenceevidence at protein level
Length666
SequenceStatuscomplete
DateCreated2001-06-20
DateModified2021-06-02

Ontological Relatives

GenesSEMA7A

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0001755 neural crest cell migration
GO:0001934 positive regulation of protein phosphorylation
GO:0005178 integrin binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007229 integrin-mediated signaling pathway
GO:0007411 axon guidance
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0021988 olfactory lobe development
GO:0030215 semaphorin receptor binding
GO:0030335 positive regulation of cell migration
GO:0031225 anchored component of membrane
GO:0045499 chemorepellent activity
GO:0045773 positive regulation of axon extension
GO:0048675 axon extension
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0050727 regulation of inflammatory response
GO:0050919 negative chemotaxis
GO:0060907 positive regulation of macrophage cytokine production
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071526 semaphorin-plexin signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001627 Sema domainDomainDomain
IPR002165 Plexin repeatRepeatRepeat
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016201 PSI domainDomainDomain
IPR027231 SemaphorinFamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR036352 Sema domain superfamilyFamilyHomologous superfamily
IPR042824 Semaphorin-7A, sema domainDomainDomain

Diseases

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