Entity Details

Primary name CRLF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75462
EntryNameCRLF1_HUMAN
FullNameCytokine receptor-like factor 1
TaxID9606
Evidenceevidence at protein level
Length422
SequenceStatuscomplete
DateCreated2004-03-01
DateModified2021-06-02

Ontological Relatives

GenesCRLF1

GO terms

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GOName
GO:0001657 ureteric bud development
GO:0004896 cytokine receptor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0043235 receptor complex
GO:0043524 negative regulation of neuron apoptotic process
GO:0070106 interleukin-27-mediated signaling pathway
GO:0097058 CRLF-CLCF1 complex
GO:2000672 negative regulation of motor neuron apoptotic process

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015152 Growth hormone/erythropoietin receptor, ligand bindingDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions