Entity Details

Primary name CBR3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75828
EntryNameCBR3_HUMAN
FullNameCarbonyl reductase [NADPH] 3
TaxID9606
Evidenceevidence at protein level
Length277
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesCBR3

GO terms

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GOName
GO:0000253 3-keto sterol reductase activity
GO:0004090 carbonyl reductase (NADPH) activity
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006805 xenobiotic metabolic process
GO:0042376 phylloquinone catabolic process
GO:0050890 cognition
GO:0070402 NADPH binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00776 OxcarbazepineDrugbanksmall molecule
DB00997 DoxorubicinDrugbanksmall molecule
DB12161 DeutetrabenazineDrugbanksmall molecule