Entity Details

Primary name NEUL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO76050
EntryNameNEUL1_HUMAN
FullNameE3 ubiquitin-protein ligase NEURL1
TaxID9606
Evidenceevidence at transcript level
Length574
SequenceStatuscomplete
DateCreated2005-03-15
DateModified2021-06-02

Ontological Relatives

GenesNEURL1

GO terms

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GOName
GO:0004842 ubiquitin-protein transferase activity
GO:0005886 plasma membrane
GO:0006513 protein monoubiquitination
GO:0007219 Notch signaling pathway
GO:0007288 sperm axoneme assembly
GO:0007399 nervous system development
GO:0007420 brain development
GO:0007519 skeletal muscle tissue development
GO:0007595 lactation
GO:0008285 negative regulation of cell population proliferation
GO:0014069 postsynaptic density
GO:0043065 positive regulation of apoptotic process
GO:0043197 dendritic spine
GO:0043204 perikaryon
GO:0045183 translation factor activity, non-nucleic acid binding
GO:0045741 positive regulation of epidermal growth factor-activated receptor activity
GO:0045746 negative regulation of Notch signaling pathway
GO:0046872 metal ion binding
GO:0048170 positive regulation of long-term neuronal synaptic plasticity
GO:0048471 perinuclear region of cytoplasm
GO:0051491 positive regulation of filopodium assembly
GO:0060999 positive regulation of dendritic spine development
GO:0061630 ubiquitin protein ligase activity
GO:0071230 cellular response to amino acid stimulus
GO:0090129 positive regulation of synapse maturation
GO:0097440 apical dendrite

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm
Perikaryon

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR006573 Neuralized homology repeat (NHR) domainDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR037962 NeuralizedFamilyFamily
IPR043136 B30.2/SPRY domain superfamilyFamilyHomologous superfamily

Diseases

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