Entity Details

Primary name S1PR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95136
EntryNameS1PR2_HUMAN
FullNameSphingosine 1-phosphate receptor 2
TaxID9606
Evidenceevidence at protein level
Length353
SequenceStatuscomplete
DateCreated2003-11-07
DateModified2021-06-02

Ontological Relatives

GenesS1PR2

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001664 G protein-coupled receptor binding
GO:0003376 sphingosine-1-phosphate receptor signaling pathway
GO:0004930 G protein-coupled receptor activity
GO:0005178 integrin binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0008289 lipid binding
GO:0008528 G protein-coupled peptide receptor activity
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0014912 negative regulation of smooth muscle cell migration
GO:0016021 integral component of membrane
GO:0019222 regulation of metabolic process
GO:0031532 actin cytoskeleton reorganization
GO:0038036 sphingosine-1-phosphate receptor activity
GO:0046847 filopodium assembly
GO:0090394 negative regulation of excitatory postsynaptic potential
GO:1903142 positive regulation of establishment of endothelial barrier
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR004061 Sphingosine 1-phosphate receptorFamilyFamily
IPR004063 EDG-5 sphingosine 1-phosphate receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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