Entity Details

Primary name COX1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP00395
EntryNameCOX1_HUMAN
FullNameCytochrome c oxidase subunit 1
TaxID9606
Evidenceevidence at protein level
Length513
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesCOX1

GO terms

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GOName
GO:0004129 cytochrome-c oxidase activity
GO:0005743 mitochondrial inner membrane
GO:0005750 mitochondrial respiratory chain complex III
GO:0005751 mitochondrial respiratory chain complex IV
GO:0006123 mitochondrial electron transport, cytochrome c to oxygen
GO:0006979 response to oxidative stress
GO:0007568 aging
GO:0009060 aerobic respiration
GO:0015990 electron transport coupled proton transport
GO:0016021 integral component of membrane
GO:0020037 heme binding
GO:0021549 cerebellum development
GO:0022904 respiratory electron transport chain
GO:0045277 respiratory chain complex IV
GO:0046688 response to copper ion
GO:0046872 metal ion binding
GO:0051602 response to electrical stimulus

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR000883 Cytochrome c oxidase subunit IFamilyFamily
IPR023615 Cytochrome c oxidase, subunit I, copper-binding siteSiteBinding site
IPR023616 Cytochrome c oxidase-like, subunit I domainDomainDomain
IPR033944 Cytochrome c oxidase subunit I domainDomainDomain
IPR036927 Cytochrome c oxidase-like, subunit I superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02659 Cholic AcidDrugbanksmall molecule
DB04464 N-FormylmethionineDrugbanksmall molecule
DB06778 Cupric sulfateSwissprotsmall molecule
DB09130 CopperDrugbanksmall molecule
DB09140 OxygenDrugbanksmall molecule