Entity Details

Primary name THBG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP05543
EntryNameTHBG_HUMAN
FullNameThyroxine-binding globulin
TaxID9606
Evidenceevidence at protein level
Length415
SequenceStatuscomplete
DateCreated1988-11-01
DateModified2021-06-02

Ontological Relatives

GenesSERPINA7

GO terms

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GOName
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0010951 negative regulation of endopeptidase activity
GO:0070062 extracellular exosome
GO:0070327 thyroid hormone transport

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000215 Serpin familyFamilyFamily
IPR023795 Serpin, conserved siteSiteConserved site
IPR023796 Serpin domainDomainDomain
IPR036186 Serpin superfamilyFamilyHomologous superfamily
IPR042178 Serpin superfamily, domain 1FamilyHomologous superfamily
IPR042185 Serpin superfamily, domain 2FamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00023 Asparaginase Escherichia coliSwissprotbiotech
DB00059 PegaspargaseSwissprotbiotech
DB00252 PhenytoinDrugbanksmall molecule
DB00279 LiothyronineDrugbanksmall molecule
DB00286 Conjugated estrogensDrugbanksmall molecule
DB00322 FloxuridineDrugbanksmall molecule
DB00451 LevothyroxineDrugbanksmall molecule
DB00532 MephenytoinDrugbanksmall molecule
DB00544 FluorouracilDrugbanksmall molecule
DB00627 NiacinDrugbanksmall molecule
DB00636 ClofibrateDrugbanksmall molecule
DB00648 MitotaneDrugbanksmall molecule
DB00675 TamoxifenDrugbanksmall molecule
DB00695 FurosemideDrugbanksmall molecule
DB00754 EthotoinDrugbanksmall molecule
DB00939 Meclofenamic acidDrugbanksmall molecule
DB01109 HeparinDrugbanksmall molecule
DB01219 DantroleneDrugbanksmall molecule
DB01320 FosphenytoinDrugbanksmall molecule
DB01452 DiamorphineDrugbanksmall molecule
DB01583 LiotrixDrugbanksmall molecule
DB01629 5-fluorouridineDrugbanksmall molecule
DB05235 NRP409Drugbanksmall molecule
DB08886 Asparaginase Erwinia chrysanthemiSwissprotbiotech
DB08899 EnzalutamideDrugbanksmall molecule
DB08984 EtofenamateSwissprotsmall molecule
DB09100 Thyroid, porcineDrugbankbiotech
DB09130 CopperDrugbanksmall molecule
DB09256 TegafurDrugbanksmall molecule
DB09317 Synthetic Conjugated Estrogens, ADrugbanksmall molecule
DB09318 Synthetic Conjugated Estrogens, BDrugbanksmall molecule
DB09381 Esterified estrogensSwissprotsmall molecule
DB11100 AllantoinSwissprotsmall molecule
DB12425 Liothyronine I-131Swissprotsmall molecule
DB13396 NeocitrullamonSwissprotsmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
THBG_HUMANMOT8_HUMANHPRD12871948 details