Entity Details

Primary name TACD2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP09758
EntryNameTACD2_HUMAN
FullNameTumor-associated calcium signal transducer 2
TaxID9606
Evidenceevidence at protein level
Length323
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesTACSTD2

GO terms

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GOName
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005829 cytosol
GO:0007601 visual perception
GO:0009925 basal plasma membrane
GO:0010633 negative regulation of epithelial cell migration
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016328 lateral plasma membrane
GO:0050896 response to stimulus
GO:0051497 negative regulation of stress fiber assembly
GO:0070062 extracellular exosome
GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis
GO:1900025 negative regulation of substrate adhesion-dependent cell spreading
GO:1900028 negative regulation of ruffle assembly
GO:2000146 negative regulation of cell motility
GO:2000738 positive regulation of stem cell differentiation

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000716 Thyroglobulin type-1DomainDomain
IPR036857 Thyroglobulin type-1 superfamilyFamilyHomologous superfamily
IPR043406 Transmembrane glycoprotein EPCAM/Trop-2FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB12893 Sacituzumab govitecanDrugbankbiotech