Entity Details

Primary name ATF6A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP18850
EntryNameATF6A_HUMAN
FullNameCyclic AMP-dependent transcription factor ATF-6 alpha
TaxID9606
Evidenceevidence at protein level
Length670
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesATF6

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001654 eye development
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006457 protein folding
GO:0007165 signal transduction
GO:0007601 visual perception
GO:0010508 positive regulation of autophagy
GO:0016020 membrane
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0035497 cAMP response element binding
GO:0036500 ATF6-mediated unfolded protein response
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:1903893 positive regulation of ATF6-mediated unfolded protein response
GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Golgi apparatus membrane
Nucleus

Domains

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DomainNameCategoryType
IPR004827 Basic-leucine zipper domainDomainDomain
IPR029801 cAMP-dependent transcription factor ATF-6 alphaFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00852 PseudoephedrineDrugbanksmall molecule