Entity Details

Primary name CAP7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP20160
EntryNameCAP7_HUMAN
FullNameAzurocidin
TaxID9606
Evidenceevidence at protein level
Length251
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesAZU1

GO terms

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GOName
GO:0001774 microglial cell activation
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006508 proteolysis
GO:0006954 inflammatory response
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0008201 heparin binding
GO:0008233 peptidase activity
GO:0008347 glial cell migration
GO:0010628 positive regulation of gene expression
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0015643 toxic substance binding
GO:0019730 antimicrobial humoral response
GO:0019898 extrinsic component of membrane
GO:0032724 positive regulation of fractalkine production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035577 azurophil granule membrane
GO:0035578 azurophil granule lumen
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0042117 monocyte activation
GO:0042582 azurophil granule
GO:0043066 negative regulation of apoptotic process
GO:0043114 regulation of vascular permeability
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0043395 heparan sulfate proteoglycan binding
GO:0045123 cellular extravasation
GO:0045348 positive regulation of MHC class II biosynthetic process
GO:0045785 positive regulation of cell adhesion
GO:0045860 positive regulation of protein kinase activity
GO:0048246 macrophage chemotaxis
GO:0050766 positive regulation of phagocytosis
GO:0050829 defense response to Gram-negative bacterium
GO:0050930 induction of positive chemotaxis
GO:0051607 defense response to virus
GO:0060326 cell chemotaxis
GO:0070062 extracellular exosome
GO:0070528 protein kinase C signaling
GO:0070944 neutrophil-mediated killing of bacterium

Subcellular Location

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Subcellular Location
Cytoplasmic granule membrane

Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
CAP7_HUMANCLC4G_HUMANBioGRID, IntAct18624398 details
CAP7_HUMANPROP_HUMANIntAct24355864 details
CAP7_HUMANTTK_HUMANHPRD15304323 details