Entity Details

Primary name PO3F3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP20264
EntryNamePO3F3_HUMAN
FullNamePOU domain, class 3, transcription factor 3
TaxID9606
Evidenceevidence at protein level
Length500
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesPOU3F3

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007417 central nervous system development
GO:0007588 excretion
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0021799 cerebral cortex radially oriented cell migration
GO:0021869 forebrain ventricular zone progenitor cell division
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048878 chemical homeostasis
GO:0071837 HMG box domain binding
GO:0072218 metanephric ascending thin limb development
GO:0072227 metanephric macula densa development
GO:0072233 metanephric thick ascending limb development
GO:0072236 metanephric loop of Henle development
GO:0072240 metanephric DCT cell differentiation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000327 POU-specific domainDomainDomain
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR010982 Lambda repressor-like, DNA-binding domain superfamilyFamilyHomologous superfamily
IPR013847 POU domainDomainDomain
IPR016362 POU-domain transcription factor, class 3FamilyFamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

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