Entity Details

Primary name PO3F2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP20265
EntryNamePO3F2_HUMAN
FullNamePOU domain, class 3, transcription factor 2
TaxID9606
Evidenceevidence at protein level
Length443
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesPOU3F2

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0008284 positive regulation of cell population proliferation
GO:0008544 epidermis development
GO:0010629 negative regulation of gene expression
GO:0014002 astrocyte development
GO:0021799 cerebral cortex radially oriented cell migration
GO:0021869 forebrain ventricular zone progenitor cell division
GO:0021979 hypothalamus cell differentiation
GO:0021985 neurohypophysis development
GO:0022011 myelination in peripheral nervous system
GO:0030182 neuron differentiation
GO:0040018 positive regulation of multicellular organism growth
GO:0042802 identical protein binding
GO:0045595 regulation of cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048663 neuron fate commitment
GO:0048665 neuron fate specification
GO:0048666 neuron development
GO:0050770 regulation of axonogenesis
GO:0071310 cellular response to organic substance
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000327 POU-specific domainDomainDomain
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR010982 Lambda repressor-like, DNA-binding domain superfamilyFamilyHomologous superfamily
IPR013847 POU domainDomainDomain
IPR016362 POU-domain transcription factor, class 3FamilyFamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

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