Entity Details

Primary name ALAT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP24298
EntryNameALAT1_HUMAN
FullNameAlanine aminotransferase 1
TaxID9606
Evidenceevidence at protein level
Length496
SequenceStatuscomplete
DateCreated1992-03-01
DateModified2021-06-02

Ontological Relatives

GenesGPT

GO terms

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GOName
GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity
GO:0005829 cytosol
GO:0009058 biosynthetic process
GO:0009078 pyruvate family amino acid metabolic process
GO:0030170 pyridoxal phosphate binding
GO:0032869 cellular response to insulin stimulus
GO:0042594 response to starvation
GO:0042853 L-alanine catabolic process
GO:0045722 positive regulation of gluconeogenesis
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR004839 Aminotransferase, class I/classIIDomainDomain
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00142 Glutamic acidDrugbanksmall molecule
DB00160 AlanineDrugbanksmall molecule
DB00780 PhenelzineDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ALAT1_HUMANCDC7_HUMANBioGRID, IntAct21988832 details
ALAT1_HUMANCAN1_HUMANBioGRID, HPRD12358155 details