Entity Details

Primary name CNTF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26441
EntryNameCNTF_HUMAN
FullNameCiliary neurotrophic factor
TaxID9606
Evidenceevidence at protein level
Length200
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesCNTF

GO terms

Show/Hide Table
GOName
GO:0005125 cytokine activity
GO:0005127 ciliary neurotrophic factor receptor binding
GO:0005138 interleukin-6 receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0019221 cytokine-mediated signaling pathway
GO:0030424 axon
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0043524 negative regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0046533 negative regulation of photoreceptor cell differentiation
GO:0046668 regulation of retinal cell programmed cell death
GO:0048143 astrocyte activation
GO:0048644 muscle organ morphogenesis
GO:0048666 neuron development
GO:0048680 positive regulation of axon regeneration
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000151 Ciliary neurotrophic factor, CNTFFamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily

Diseases

Show/Hide Table