Entity Details

Primary name SSR4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP31391
EntryNameSSR4_HUMAN
FullNameSomatostatin receptor type 4
TaxID9606
Evidenceevidence at transcript level
Length388
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesSSTR4

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0004994 somatostatin receptor activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007218 neuropeptide signaling pathway
GO:0008285 negative regulation of cell population proliferation
GO:0016477 cell migration
GO:0030900 forebrain development
GO:0042277 peptide binding
GO:0042923 neuropeptide binding
GO:0043005 neuron projection
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071385 cellular response to glucocorticoid stimulus
GO:0090238 positive regulation of arachidonic acid secretion
GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000586 Somatostatin receptor familyFamilyFamily
IPR001512 Somatostatin receptor 4FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB09099 SomatostatinDrugbanksmall molecule
DB13985 Lutetium Lu 177 dotatateDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
SSR4_HUMANCORT_HUMANBioGRID, HPRD9125122 9205124 details
SSR4_HUMANOPRD_HUMANBioGRID24416361 details
SSR4_HUMANSMS_HUMANHPRD8100352 details