Entity Details

Primary name IFNA8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP32881
EntryNameIFNA8_HUMAN
FullNameInterferon alpha-8
TaxID9606
Evidenceevidence at protein level
Length189
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesIFNA8

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0002286 T cell activation involved in immune response
GO:0002323 natural killer cell activation involved in immune response
GO:0005125 cytokine activity
GO:0005126 cytokine receptor binding
GO:0005132 type I interferon receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006959 humoral immune response
GO:0007596 blood coagulation
GO:0019221 cytokine-mediated signaling pathway
GO:0030183 B cell differentiation
GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein
GO:0042100 B cell proliferation
GO:0043330 response to exogenous dsRNA
GO:0051607 defense response to virus
GO:0060337 type I interferon signaling pathway

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000471 Interferon alpha/beta/deltaFamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
IFNA8_HUMANGP152_HUMANBioGRID, IntAct32296183 details
IFNA8_HUMANA4_HUMANBioGRID21832049 details
IFNA8_HUMANINAR2_HUMANHPRD8969169 details