Entity Details

Primary name APJ_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35414
EntryNameAPJ_HUMAN
FullNameApelin receptor
TaxID9606
Evidenceevidence at protein level
Length380
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesAPLNR

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001568 blood vessel development
GO:0001570 vasculogenesis
GO:0001944 vasculature development
GO:0001947 heart looping
GO:0003171 atrioventricular valve development
GO:0003272 endocardial cushion formation
GO:0004930 G protein-coupled receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007369 gastrulation
GO:0007507 heart development
GO:0007512 adult heart development
GO:0010468 regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016032 viral process
GO:0031065 positive regulation of histone deacetylation
GO:0035886 vascular associated smooth muscle cell differentiation
GO:0035904 aorta development
GO:0038023 signaling receptor activity
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0045766 positive regulation of angiogenesis
GO:0050878 regulation of body fluid levels
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0060182 apelin receptor activity
GO:0060183 apelin receptor signaling pathway
GO:0060412 ventricular septum morphogenesis
GO:0060841 venous blood vessel development
GO:0060976 coronary vasculature development
GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:1903596 regulation of gap junction assembly
GO:1904325 positive regulation of inhibitory G protein-coupled receptor phosphorylation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR003904 Apelin receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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