Entity Details

Primary name RGS2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP41220
EntryNameRGS2_HUMAN
FullNameRegulator of G-protein signaling 2
TaxID9606
Evidenceevidence at protein level
Length211
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesRGS2

GO terms

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GOName
GO:0001965 G-protein alpha-subunit binding
GO:0001975 response to amphetamine
GO:0005096 GTPase activator activity
GO:0005516 calmodulin binding
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007049 cell cycle
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007283 spermatogenesis
GO:0007420 brain development
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0009898 cytoplasmic side of plasma membrane
GO:0010519 negative regulation of phospholipase activity
GO:0010614 negative regulation of cardiac muscle hypertrophy
GO:0010976 positive regulation of neuron projection development
GO:0017148 negative regulation of translation
GO:0030728 ovulation
GO:0043005 neuron projection
GO:0043407 negative regulation of MAP kinase activity
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0045471 response to ethanol
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway
GO:0048487 beta-tubulin binding
GO:0050873 brown fat cell differentiation
GO:0055119 relaxation of cardiac muscle
GO:0060087 relaxation of vascular associated smooth muscle
GO:0060135 maternal process involved in female pregnancy
GO:0060452 positive regulation of cardiac muscle contraction
GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development
GO:0140194 negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
GO:1900924 negative regulation of glycine import across plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR016137 RGS domainDomainDomain
IPR024066 RGS, subdomain 1/3FamilyHomologous superfamily
IPR034947 Regulator of G-protein signalling 2FamilyFamily
IPR036305 RGS domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

71 interactions

InteractorPartnerSourcesPublicationsLink
RGS2_HUMANGIT1_HUMANBioGRID, HPRD, IntAct, MINT16169070 21900206 details
RGS2_HUMANDDR1_HUMANBioGRID, HPRD, IntAct, MINT16169070 21900206 details
RGS2_HUMANHSP7C_HUMANBioGRID, HPRD, IntAct, MINT16169070 21900206 details
RGS2_HUMANARFG1_HUMANBioGRID, HPRD, IntAct16169070 details
RGS2_HUMANDYL1_HUMANBioGRID, HPRD, IntAct, MINT16169070 21900206 details
RGS2_HUMANPRKN_HUMANBioGRID, HPRD, IntAct, MINT16169070 21900206 32814053 details
RGS2_HUMANGLU2B_HUMANBioGRID, HPRD, IntAct, MINT16169070 21900206 details
RGS2_HUMANWDR74_HUMANBioGRID, HPRD, IntAct, MINT16169070 21900206 details
RGS2_HUMANLRFN1_HUMANBioGRID, IntAct, MINT16169070 21900206 details
RGS2_HUMANNIPS1_HUMANBioGRID, HPRD, IntAct, MINT16169070 21900206 details
RGS2_HUMANVPS29_HUMANBioGRID, HPRD, IntAct, MINT16169070 21900206 details
RGS2_HUMANCATB_HUMANBioGRID, HPRD, IntAct, MINT16169070 21900206 details
RGS2_HUMANSCN5A_HUMANHPRD, IntAct16169070 details
RGS2_HUMANNINL_HUMANBioGRID, HPRD, IntAct16189514 28514442 details
RGS2_HUMANNEB1_HUMANMINT17464283 details
RGS2_HUMANCLCA_HUMANBioGRID, IntAct21988832 details
RGS2_HUMANRAP1B_HUMANBioGRID, IntAct21988832 details
RGS2_HUMANFZD5_HUMANBioGRID, IntAct21988832 details
RGS2_HUMANKLK8_HUMANBioGRID, IntAct21988832 details
RGS2_HUMANBBS10_HUMANBioGRID, MINT21900206 details
RGS2_HUMANMET18_HUMANBioGRID, MINT21900206 details
RGS2_HUMANCHD3_HUMANBioGRID, MINT21900206 details
RGS2_HUMANCOMT_HUMANBioGRID, MINT21900206 details
RGS2_HUMANDPYL1_HUMANBioGRID, MINT21900206 details
RGS2_HUMANDUS21_HUMANBioGRID, MINT21900206 details
RGS2_HUMANEIF3L_HUMANBioGRID, MINT21900206 details
RGS2_HUMANIR3IP_HUMANBioGRID, MINT21900206 details
RGS2_HUMANHAUS5_HUMANBioGRID, MINT21900206 details
RGS2_HUMANCE126_HUMANBioGRID, MINT21900206 details
RGS2_HUMANDNLI1_HUMANBioGRID, MINT21900206 details
RGS2_HUMANMON1A_HUMANBioGRID, MINT21900206 details
RGS2_HUMANRAB2A_HUMANBioGRID, MINT21900206 details
RGS2_HUMANPRAF1_HUMANBioGRID, MINT21900206 details
RGS2_HUMANREEP5_HUMANBioGRID, MINT21900206 details
RGS2_HUMANRIN3_HUMANBioGRID, MINT21900206 details
RGS2_HUMANTSN15_HUMANBioGRID, MINT21900206 details
RGS2_HUMANTBB2B_HUMANBioGRID, MINT21900206 details
RGS2_HUMANUBC_HUMANBioGRID, MINT21900206 details
RGS2_HUMANXRCC6_HUMANBioGRID, MINT21900206 details
RGS2_HUMANTZAP_HUMANBioGRID, MINT21900206 details
RGS2_HUMANZN579_HUMANBioGRID, MINT21900206 details
RGS2_HUMANZYX_HUMANBioGRID, MINT21900206 details
RGS2_HUMANLRRK2_HUMANIntAct24794857 details
RGS2_HUMANMTUS2_HUMANBioGRID, IntAct25416956 25910212 details
RGS2_HUMANCIAO1_HUMANBioGRID, IntAct32296183 details
RGS2_HUMANMARH6_HUMANBioGRID, DIP25766235 30425097 details
RGS2_HUMANKGP1_HUMANBioGRID, HPRD14608379 details
RGS2_HUMANGNA15_HUMANBioGRID, HPRD12885252 details
RGS2_HUMANGNAQ_HUMANBioGRID, HPRD12885252 9405622 details
RGS2_HUMANADCY5_HUMANBioGRID, HPRD12604604 details
RGS2_HUMANGNAI3_HUMANBioGRID9079700 details
RGS2_HUMANCOPB2_HUMANBioGRID, HPRD10982407 details
RGS2_HUMANKPCA_HUMANBioGRID, HPRD11063746 details
RGS2_HUMANKPCB_HUMANBioGRID, HPRD11063746 details
RGS2_HUMANKPCG_HUMANBioGRID, HPRD11063746 details
RGS2_HUMANGDE1_HUMANBioGRID, HPRD10760272 details
RGS2_HUMANGNAS3_HUMANBioGRID9794454 details
RGS2_HUMANGNAS2_HUMANBioGRID, HPRD9794454 details
RGS2_HUMANALEX_HUMANBioGRID9794454 details
RGS2_HUMANGNAS1_HUMANBioGRID, HPRD9794454 details
RGS2_HUMANADRB2_HUMANBioGRID24561123 details
RGS2_HUMANEGFR_HUMANBioGRID11602604 details
RGS2_HUMANFBX44_HUMANBioGRID25970626 details
RGS2_HUMANDDB1_HUMANBioGRID25970626 details
RGS2_HUMANCUL4B_HUMANBioGRID28974581 details
RGS2_HUMANCOPB_HUMANHPRD10982407 details
RGS2_HUMANCALM1_HUMANHPRD10747990 details
RGS2_HUMANCALM2_HUMANHPRD10747990 details
RGS2_HUMANCALM3_HUMANHPRD10747990 details
RGS2_HUMANADA1A_HUMANHPRD15917235 details
RGS2_HUMANNEB2_HUMANHPRD17464283 details