Entity Details

Primary name GLR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP47871
EntryNameGLR_HUMAN
FullNameGlucagon receptor
TaxID9606
Evidenceevidence at protein level
Length477
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesGCGR

GO terms

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GOName
GO:0004967 glucagon receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006091 generation of precursor metabolites and energy
GO:0007166 cell surface receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007584 response to nutrient
GO:0008217 regulation of blood pressure
GO:0008528 G protein-coupled peptide receptor activity
GO:0009267 cellular response to starvation
GO:0010628 positive regulation of gene expression
GO:0016021 integral component of membrane
GO:0017046 peptide hormone binding
GO:0042593 glucose homeostasis
GO:0042594 response to starvation
GO:0070873 regulation of glycogen metabolic process
GO:0071377 cellular response to glucagon stimulus

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001879 GPCR, family 2, extracellular hormone receptor domainDomainDomain
IPR003290 GPCR, family 2, glucagon-like peptide-1/glucagon receptorFamilyFamily
IPR003291 GPCR, family 2, glucagon receptorFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR017983 GPCR, family 2, secretin-like, conserved siteSiteConserved site
IPR036445 GPCR family 2, extracellular hormone receptor domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00040 GlucagonDrugbankbiotech