Entity Details

Primary name P2RY1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP47900
EntryNameP2RY1_HUMAN
FullNameP2Y purinoceptor 1
TaxID9606
Evidenceevidence at protein level
Length373
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesP2RY1

GO terms

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GOName
GO:0001621 G protein-coupled ADP receptor activity
GO:0001934 positive regulation of protein phosphorylation
GO:0001973 G protein-coupled adenosine receptor signaling pathway
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005929 cilium
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007568 aging
GO:0008347 glial cell migration
GO:0008360 regulation of cell shape
GO:0009612 response to mechanical stimulus
GO:0009986 cell surface
GO:0010469 regulation of signaling receptor activity
GO:0010700 negative regulation of norepinephrine secretion
GO:0014069 postsynaptic density
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0019233 sensory perception of pain
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030168 platelet activation
GO:0030425 dendrite
GO:0031686 A1 adenosine receptor binding
GO:0032962 positive regulation of inositol trisphosphate biosynthetic process
GO:0038023 signaling receptor activity
GO:0042755 eating behavior
GO:0043270 positive regulation of ion transport
GO:0043531 ADP binding
GO:0044297 cell body
GO:0045028 G protein-coupled purinergic nucleotide receptor activity
GO:0045031 G protein-coupled ATP receptor activity
GO:0045211 postsynaptic membrane
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046887 positive regulation of hormone secretion
GO:0046982 protein heterodimerization activity
GO:0051100 negative regulation of binding
GO:0060406 positive regulation of penile erection
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070848 response to growth factor
GO:0071318 cellular response to ATP
GO:0071415 cellular response to purine-containing compound
GO:0072659 protein localization to plasma membrane
GO:0090075 relaxation of muscle
GO:0097110 scaffold protein binding
GO:0097746 blood vessel diameter maintenance
GO:0098978 glutamatergic synapse
GO:0099059 integral component of presynaptic active zone membrane
GO:0099509 regulation of presynaptic cytosolic calcium ion concentration
GO:2000300 regulation of synaptic vesicle exocytosis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000142 P2Y purinoceptor 1FamilyFamily
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01069 PromethazineDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
P2RY1_HUMANNHRF1_HUMANBioGRID, HPRD, MINT9671706 details
P2RY1_HUMANAA1R_HUMANBioGRID, HPRD11390975 details
P2RY1_HUMANNHRF2_HUMANHPRD9671706 details